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Grinder Fission

(f) Tip cap removed, and packed fission yeast swiftly extruded into liquid nitrogen (blue) as a continuous bead or “noodle”. (g) Noodle broken into 3- to 7-mm pieces in liquid nitrogen. (h) Pieces loaded into pre-cooled (liquid nitrogen) motorized precision mortar grinder and ground in liquid nitrogen at the minimum pressure setting ( 0”)

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